Nickel‐Catalyzed Carboxylation of Benzylic C−N Bonds with CO2 |
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| Authors: | Dr Toni Moragas Dr Morgane Gaydou Prof Ruben Martin |
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| Institution: | 1. Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology, Tarragona, Spain;2. Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain |
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| Abstract: | A user‐friendly Ni‐catalyzed reductive carboxylation of benzylic C?N bonds with CO2 is described. This procedure outperforms state‐of‐the‐art techniques for the carboxylation of benzyl electrophiles by avoiding commonly observed parasitic pathways, such as homodimerization or β‐hydride elimination, thus leading to new knowledge in cross‐electrophile reactions. |
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| Keywords: | carboxylation C− N activation homogeneous catalysis nickel reductive coupling |
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