“On–off–on” pyrene-based fluorescent chemosensor for the selective recognition of Cu2+ and S2− ions and its utilization in live cell imaging |
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Authors: | Dhivya Rajasekaran Kavitha Venkatachalam Viswanathamurthi Periasamy |
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Institution: | Department of Chemistry, Periyar University, Salem, -636 011, India |
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Abstract: | A new “on–off–on” fluorescence chemosensor (DPD) was designed, synthesized, and characterized based on pyrene and benzothiozole hydrazide. The probe DPD shows high affinity towards Cu2+ ions and the DPD-Cu2+ ensemble shows high sensitivity towards S2− ions through the displacement method in the presence of other interfering ions. The detection limits of DPD for Cu2+ and S2− ions were found to be 0.73 and 0.87 nM, respectively. Furthermore, the receptor was effectively applied to recognize Cu2+ and S2− ions in real samples and live A549 cells through imaging studies. |
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Keywords: | copper ion detection fluorescent probe live cell imaging real water sample analysis |
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