A Rapid Access to Novel and Known Benzimidazole Derivatives Using Silica Chloride as a Reusable Catalyst |
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| Authors: | Bahador Karami Vahideh Ghashghaee Saeed Khodabakhshi |
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| Institution: | 1. Department of Chemistry, Yasouj University, Yasouj, Zip Code: 75918‐74831, P.O.Box 353, Iran;2. Department of Chemistry, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran |
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| Abstract: | A new application of silica chloride as an easily available and reusable solid acid catalyst for the synthesis of benzimidazole and its derivatives through the condensation of o‐phenylenediamines and orthoesters under thermal and solvent‐free conditions is described. This novel and eco‐friendly method is very cheap and has many advantages including excellent yields, short reaction time, and simple work‐up procedure. |
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| Keywords: | silica chloride orthoesters o‐phenylenediamine benzimidazole |
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