A new flavanone glycoside isolated from Tournefortia sibirica |
| |
| Authors: | Shengbao Diao Mei Jin Chun Shi Jin Cheng-Xi Wei Jinfeng Sun |
| |
| Institution: | 1. Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University College of Pharmacy, Yanji, China;2. Department of Pharmacy, Yanbian University Hospital, Yanji, China;3. Medical College, Inner Mongolia University for Nationalities, Tongliao, China |
| |
| Abstract: | A new flavanone glycoside, (2S)-dihydrooroxylin A 7-O-β-D-apiosyl(1→2)]-β-D-glucoside (1), and four known compounds (2–5) were isolated from Tournefortia sibirica L. The chemical structures of these compounds were determined by 1?D and 2?D NMR and HR-ESI-MS spectra, and results were compared with data from the literature. These five compounds (1–5) were isolated from the family Boraginaceae for the first time. Anti-inflammatory effects of compounds (1–5) were evaluated in terms of inhibition of production of NO, TNF-α, and IL-6 in LPS-induced RAW 264.7 cells. |
| |
| Keywords: | Tournefortia sibirica L Boraginaceae flavanone glycoside |
|
|
