New compound from Euphorbia alatavica Boiss |
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| Authors: | Rushangul Rozimamat Nurmuhammat Kehrimen |
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| Institution: | 1. Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, China;2. University of the Chinese Academy of Sciences, Beijing, China;3. State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, China |
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| Abstract: | One new compound alatavinol (1), together with five known compounds, kaempferol (2), quercetin (3), laricircsinol (4), secoisolariciresinol (5) and loliolide (6) were isolated from the whole plant of Euphorbia alatavica Boiss. Those compounds were isolated and purified by various column chromatographic methods and their structures were elucidated by spectroscopic (1D, 2D NMR, and HR-MS) chemical analyses. All compounds were isolated for the first time from E. alatavica Boiss, and biochemical pathway of the new compound has been hypothesized. Furthermore, these compounds were evaluated for antioxidant properties based on the DPPH radical scavenging activities. Results showed that IC50 values of compounds 1, 3, 4, 5 and 6 were 25.69, 1.88, 2.87, 11.55 and 17.81 μg/mL, respectively, as compared to the control ascorbic acid (5.34 μg/mL). |
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| Keywords: | Euphorbia alatavica isolation DPPH radical scavenging activities |
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