Chemical composition,antimicrobial and antioxidant activities of the essential oils of three Uzbek Lamiaceae species |
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| Authors: | Nilufar Z. Mamadalieva Fadia S. Youssef Mohamed L. Ashour Sobirdjan A. Sasmakov Antonio Tiezzi Shahnoz S. Azimova |
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| Affiliation: | 1. Institute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, Uzbekistan;2. Faculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, Cairo, Egypt;3. Department for the Innovation in Biological, Agro-food and Forestal Systems, Tuscia University, Viterbo, Italy |
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| Abstract: | The chemical composition of the essential oil from the aerial parts of three Lamiaceae species from Uzbekistan was investigated by GC-MS analysis. β-Linalool (26.6%), α-terpineol (10.0%), coumarin (8.9%) and 4,5,7,7α-tetrahydro-4,4,7α-trimethyl-2(6H)-benzofuranone (5.4%) resulted as the main components of Ajuga turkestanica essential oil, while camphene (17.1%), 1,8-cineole (15.9%), β-cymene (7.9%) and limonene (7.4%) in Phlomis regelii. The essential oil of Thymus seravschanicus was dominated by thymol (37.5%), phellandral (26.0%), τ-terpinene (6.6%) and β-cymene (5.2%). The essential oils had considerable antimicrobial activity against different bacterial strains and fungi. Among the tested samples of essential oils, P. regelii essential oil has the significant antioxidant activity with IC50 value of 117.8 ± 8.02 μg/mL. |
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| Keywords: | Lamiaceae Uzbek Flora essential oils GC-MS antimicrobial antioxidant |
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