Synthesis of methyl (5Z,8Z,10E,12E,14Z)-eicosapentaenoate |
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| Authors: | Yasser MA MohamedTrond Vidar Hansen |
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| Institution: | School of Pharmacy, Department of Pharmaceutical Chemistry, University of Oslo, PO Box 1068, Blindern, N-0316 Oslo, Norway |
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| Abstract: | The first total synthesis of methyl (5Z,8Z,10E,12E,14Z)-eicosapentaenoate has been achieved in seven steps and in 16% overall yield. The synthesis confirmed the assigned structure of this polyunsaturated natural product. |
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| Keywords: | Bosseopentaenoic acid MIDA-protected boronate ester Polyunsaturated fatty acid Conjugated Z E E Z-tetraene |
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