Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization |
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| Authors: | Timothy L. Kline |
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| Affiliation: | The Center for Micromagnetics and Information Technologies, Department of Electrical and Computer Engineering, University of Minnesota, US |
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| Abstract: | A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory. |
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| Keywords: | Hyperthermia Cancer treatment Tumor cell Magnetic fluid Nanoparticles Core-shell Specific absorption rate Physical vapor deposition High-moment Au shell |
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