Synthesis and Characterization of a Series of Water Soluble Amidomalonato-(lR,2R-Cyclohexanediamine)Platinum(II) Complexes |
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Abstract: | Abstract A new series of water soluble platinum(II) complexes of the type Pt(DACH)R-CH(COO)2]], wherein DACH represents IR,2R-cyclohexanediamine and R represents formamido. acetamido, (penta-O-acctyl-gluconyl)amino, and gluconylamino have been synthesized. The modes of binding of amidodicarboxylic acid derivatives in these complexes have been determined by various spectroscopic techniques: 1H, 13 C, and 195PtNMR; 2D-COSY{1H-1H} and 2D-HETCOSY{1H-13C} NMR, MS(FAB), IR and conductivity measurements. |
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Keywords: | Platinum(II) complexes diamine bioactivity NMR IR |
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