首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Parametric multiple sequence alignment and phylogeny construction
Authors:David Fernndez-Baca  Timo Sepplinen  Giora Slutzki
Institution:a Department of Computer Science, Iowa State University, Ames, IA 50011, USA;b Department of Mathematics, University of Wisconsin-Madison, Madison, WI 53706, USA
Abstract:Bounds are given on the size of the parameter-space decomposition induced by multiple sequence alignment problems where phylogenetic information may be given or inferred. It is shown that many of the usual formulations of these problems fall within the same integer parametric framework, implying that the number of distinct optima obtained as the parameters are varied across their ranges is polynomially bounded in the length and number of sequences.
Keywords:Alignment  Computational biology  Evolutionary tree  Multiple alignment  Phylogenetic tree  Sensitivity analysis
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号