Alpha-glucosidase inhibitors from Millettia conraui |
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Authors: | Tiabou Tchinda Alembert Nahar Khan Shamsun Fuendjiep Victorine Ngandeu François Ngono Ngane Annie Choudhary Muhammad Iqbal |
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Institution: | Center of Medicinal Plants Studies and Traditional Medicine (CRPMT), Institute of Medical Research and Medicinal Plants Studies (IMPM), Yaaoundé, Cameroon. alembertt2002@yahoo.fr |
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Abstract: | A new geranylated isoflavone, 7-O-geranyl-6-methoxypseudobaptigenin (1) was isolated from the stem barks of Millettia conraui, along with known compounds 5-methoxydurmillone (2), conrauinone A (3), beta-amyrine (4), sitosterol (5), 3-O-beta-D-glucopyranosyl sitosterol (6) and n-docosanol (7). Compounds 1 and 4 showed a significant alpha-glucosidase inhibitory activity. The structures of the compounds were determined by analysis of their spectroscopic data. |
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