A new bis-andrographolide ether from Andrographis paniculata nees and evaluation of anti-HIV activity |
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| Authors: | Reddy V L Niranjan Reddy S Malla Ravikanth V Krishnaiah P Goud T Venkateshwar Rao T P Ram T Siva Gonnade Rajesh G Bhadbhade Mohan Venkateswarlu Y |
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| Institution: | Natural Products Laboratory, Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India. |
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| Abstract: | Novel bis-andrographolide ether (1) and six known compounds andrographolide, 14-deoxy-11,12-didehydroandrographolide, andrograpanin, 14-deoxyandrographolide, (+/-)-5-hydroxy-7,8-dimethoxyflavanone, and 5-hydroxy-7,8-dimethoxyflavone have been isolated from the aerial parts of Andrographis paniculata and their structures were established by spectral data. All the isolates were tested for the anti-HIV and cytotoxic activity. |
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