Rhodium‐Catalyzed Asymmetric Intramolecular Hydroamination of Allenes |
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| Authors: | Dino Berthold Arne G A Geissler Sabrina Giofr Bernhard Breit |
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| Institution: | Dino Berthold,Arne G. A. Geissler,Sabrina Giofré,Bernhard Breit |
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| Abstract: | The rhodium‐catalyzed asymmetric intramolecular hydroamination of sulfonyl amides with terminal allenes is reported. It provides selective access to 5‐ and 6‐membered N‐heterocycles, scaffolds found in a large range of different bioactive compounds. Moreover, gram scale reactions, as well as the application of suitable product transformations to natural products and key intermediates thereof are demonstrated. |
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| Keywords: | Allene Allylprodukte Asymmetrische Katalyse Heterocyclen Rhodium |
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