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Eight‐Step Total Synthesis of Phalarine by Bioinspired Oxidative Coupling of Indole and Phenol |
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| Authors: | Lei Li Kuo Yuan Qianlan Jia Yanxing Jia |
| Abstract: | We report for the first time that the benzofuro[3,2‐b]indoline framework could be obtained by PIDA‐mediated direct oxidative coupling of 2,3‐disubstituted‐indoles with phenols. Application of this chemistry allows for an eight‐step total synthesis of phalarine from commercially available tryptamine. |
| Keywords: | Alkaloide Naturprodukte Oxidative Kupplung Regioselektivitä t Totalsynthese |