General remarks on the thermal decomposition of some drugs

The thermal decomposition of antituberculous, local anaesthetic and calcium salts of organic acids used as the drugs has been studied by differential thermal and thermogravimetric techniques. General characteristics of their thermal decomposition has been made. The effect of sample size over the range 20–200 mg and heating rate over the range 3–15 deg·min^?1 on the thermal degradation has been investigated. The values of the kinetic parameters has been also determined.