A Supramolecular Approach to Antimicrobial Surfaces |
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| Authors: | Valentina Gazzola Pietro Grisoli Valeria Amendola Giacomo Dacarro Carlo Mangano Piersandro Pallavicini Antonio Poggi Silvia Rossi Barbara Vigani Angelo Taglietti |
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| Affiliation: | 1.Department of Chemistry, University of Pavia, Viale Torquato Taramelli 12, 27100 Pavia, Italy;2.Department of Drug Sciences, University of Pavia, Viale Torquato Taramelli 12, 27100 Pavia, Italy |
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| Abstract: | ![]()
In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal example of an antimicrobial surface based on a supramolecular approach, obtaining a neat microbicidal effect using low amounts of the described copper complex. |
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| Keywords: | copper complexes microbicidal effect self-assembled monolayers surface functionalization antibacterial surfaces supramolecular complex cascade complexes |
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