Synthesis and network structure of ionic poly(N,N-dimethylacrylamide-co-acrylamide) hydrogels: Comparison of swelling degree with theory

At four different charge densities, ionic hydrogels based on N,N-dimethylacrylamide (DMAAm), acrylamide (AAm), and itaconic acid (IA) were synthesized by free-radical cross-linking copolymerization in water with N,N-methylenebis(acrylamide) (BAAm) as the cross-linker, ammonium persulfate (APS) as the initiator, and N,N,N′,N′-tetramethylenediamine (TEMED) as the activator. The swelling behaviors of these hydrogels were analyzed in buffer solutions at various pH. It was observed that the swelling behavior of cross-linked ionic poly(N,N-dimethylacrylamide-co-acrylamide) [P(DMAAm-co-AAm)] hydrogels at different pHs agreed with the modified Flory-Rehner equation based both on the phantom network and affine network models and the ideal Donnan theory. In addition, the kinetics of swelling of the hydrogels was studied in pH 2, 5 and 9 buffer solutions. The swelling curves exhibited the characteristic features of transport process, apparently the Fickian diffusion of fast rates.