|
|||||
|
|
Catalytic asymmetric synthesis of spirooxindoles by a mannich-type reaction of isothiocyanato oxindoles |
|
| Authors: | Kato Shota Yoshino Tatsuhiko Shibasaki Masakatsu Kanai Motomu Matsunaga Shigeki |
| Affiliation: | Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Japan. |
| Abstract: | Easy access: a strontium/Schiff base complex as catalyst for the title reaction provided straightforward access to enantiomerically enriched spiro[imidazolidine-4,3'-oxindole] compounds, as well as a spiro[imidazoline-4,3'-oxindole] through a two-step conversion from the Mannich adduct. |
| Keywords: | asymmetric catalysis asymmetric synthesis Mannich reaction oxindoles salen |
| 本文献已被 PubMed 等数据库收录！ | |