Neuromodulation by soy diets or equol: Anti-depressive &; anti-obesity-like influences,age- &; hormone-dependent effects |
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| Authors: | Crystal Blake Kimberly M Fabick Kenneth DR Setchell Trent D Lund Edwin D Lephart |
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| Affiliation: | (1) Department of Physiology and Developmental Biology and The Neuroscience Center, Brigham Young University, Provo, Utah 84602, USA;(2) Division of Pathology and Laboratory Medicine, Clinical Mass Spectrometry, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 45229, USA;(3) Stoelting Co, 620 Wheat Lane, Wood Dale, Illinois 60191, USA |
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| Abstract: | ![]()
Background Soy-derived isoflavones potentially protect against obesity and depression. In five different studies we examined the influence of soy-containing diets or equol injections on depression, serotonin levels, body weight gain (BW) and white adipose tissue (WAT) deposition in female Long-Evans rats at various stages of life [rats were intact, ovariectomized or experienced natural ovarian failure (NOF)]. |
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