1. Department of Chemistry, Durham University, South Road, Durham, DH1 3LE (UK), Fax: (+44)?191‐384‐4737 http://www.dur.ac.uk/chemistry/staff/profile/?id=194;2. Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong (China), Fax: (+852)?2358‐1594 http://ihome.ust.hk/～chzlin
Abstract:
A simple but effective copper‐catalyzed borylation of aryl halides, including electron‐rich and sterically hindered aryl bromides, with alkoxy diboron reagents occurs under mild conditions (see scheme). Preliminary DFT studies of the mechanism suggest that σ‐bond metathesis between a copper–boryl intermediate and the aryl halide generates the aryl boronate product.
