The Renaissance of α‐Methylene‐γ‐butyrolactones: New Synthetic Approaches |
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Authors: | Russell?R?A Kitson Alessia Millemaggi Richard?J?K Taylor |
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Institution: | Department of Chemistry, University of York, Heslington, York, YO10 5DD (UK) http://www.york.ac.uk/chemistry/staff/academic/t‐z/rtaylor/ |
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Abstract: | The amount of research activity concerning α‐methylene‐γ‐butyrolactones and α‐alkylidene‐γ‐butyrolactones has increased dramatically in recent years. This Review summarizes the structural types, biological activities, and biosynthesis of these compounds, concentrating on publications from the past 10 years. Traditional approaches to α‐methylene‐γ‐butyrolactones and α‐alkylidene‐γ‐butyrolactones are then reviewed together with novel approaches, including those from our own research group, reported more recently. |
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Keywords: | bioactivity biosynthesis natural products α ‐alkylidene‐γ ‐butyrolactones α ‐methylene‐γ ‐butyrolactones |
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