(1) Institute of Experimental Pharmacology, Slovak Academy of Sciences, Centre of Physiological Sciences, Dúbravská cesta 2, 842 16 Bratislava, (Czechoslovakia);(2) Research Institute of Drugs, Horná 36, 900 01 Modra, (Czechoslovakia)
Abstract:
An HPLC method was developed for studying the stability of [3H] stobadin stored in physiological saline or buffers at various pH. Optimum conditions for the separation of degradation products were elaborated. A high-performance liquid chromatograph equipped with a radioactivity detector was used.