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Facile one-pot synthesis,butyrylcholinesterase and α-glucosidase inhibitory activities,structure–activity relationship,molecular docking and DNA–drug binding analysis of Meldrum’s acid derivatives |
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| Authors: | Mehfooz Haroon Saeed Aamer Faisal Muhammad Larik Fayaz Ali Muqadar Urooj Khatoon Saira Channar Pervaiz Ali Ismail Hammad Bilquees Salma Rashid Sajid Shafique Shagufta Mirza Bushra Dilshad Erum Ahmad Fawad |
| Institution: | 1.Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan ;2.Department of Biochemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan ;3.Department of Biochemistry and Molecular Biology, University of Gujrat, Gujrat, 50700, Pakistan ;4.National Centre for Bioinformatics, Quaid-I-Azam University, Islamabad, 45320, Pakistan ; |
| Abstract: | Research on Chemical Intermediates - Meldrum’s acid derivatives were facile synthesized by one-pot condensation process and characterized by NMR (1H, 13C, DEPT-90 and DEPT-135) and EI-MS. The... |
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