Ring-Closing Metathesis of Functionalized Acetylene Derivatives: A New Entry into Cycloalkynes |
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Authors: | Alois Fü rstner,Gü nter Seidel |
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Abstract: | A tungsten alkylidyne catalyst is the key to achieving ring-closing metatheses of diynes to form functionalized macrocycles [Eq. (a)]. Partial reduction of the cycloalkynes provides stereoselective Z-configured cycloalkenes, which are currently inaccessible by conventional alkene metathesis. |
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Keywords: | Alkylidyne complexes Alkynes Macrocycles Metathesis Tungsten |
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