|
|||||
|
|
X-Ray Structure of Bacteriorhodopsin at 2.5 Å Resolution |
|
| Authors: | Ferdinand Hucho |
| Abstract: | Microfocussed X-rays produced by an electron synchrotron were essential for the first structure elucidation of protein crystals having extremely small dimensions (5×20–40 μm). A further prerequisite for the successful crystal structure analysis of bacteriorhodopsin was a novel crystallization method using a lipid matrix. These methodological breakthroughs pave the way for further advances in structure determinations of membrane proteins. |
| Keywords: | Bacteriorhodopsin Membrane proteins Protein structures Proton transfer Structure elucidation |