Multicomponent catalytic asymmetric aziridination of aldehydes |
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Authors: | Gupta Anil K Mukherjee Munmun Wulff William D |
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Institution: | Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA. |
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Abstract: | The first multicomponent catalytic asymmetric aziridination reaction is developed to give aziridine-2-carboxylic esters with very high diastereo- and enantioselectivity from aromatic and aliphatic aldehydes. This new method pushes the boundary of the aziridination reaction to substrates that failed with preformed imines. |
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