A Review: Halogenated Compounds from Marine Actinomycetes |
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| Authors: | Cong Wang Weisheng Du Huanyun Lu Jianzhou Lan Kailin Liang Shugeng Cao |
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| Institution: | 1.Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi University for Nationalities, Nanning 530006, China; (W.D.); (H.L.); (J.L.); (K.L.);2.Department of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, Hilo, HI 96720, USA |
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| Abstract: | Marine actinomycetes, Streptomyces species, produce a variety of halogenated compounds with diverse structures and a range of biological activities owing to their unique metabolic pathways. These halogenated compounds could be classified as polyketides, alkaloids (nitrogen-containing compounds) and terpenoids. Halogenated compounds from marine actinomycetes possess important biological properties such as antibacterial and anticancer activities. This review reports the sources, chemical structures and biological activities of 127 new halogenated compounds originated mainly from Streptomyces reported from 1992 to 2020. |
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| Keywords: | marine actinomycetes natural products chemical structures halogenated compounds |
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