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Drying Effects on Chemical Composition and Antioxidant Activity of Lippia thymoides Essential Oil,a Natural Source of Thymol
Authors:Lidiane Diniz do Nascimento  Sebastio Gomes Silva  Mrcia Moraes Cascaes  Kauê Santana da Costa  Pablo Luis Baia Figueiredo  Cristiane Maria Leal Costa  Eloisa Helena de Aguiar Andrade  Lênio Jos Guerreiro de Faria
Abstract:Leaves of Lippia thymoides (Verbenaceae) were dried in an oven at 40, 50 and 60 °C and the kinetic of drying and the influence of the drying process on the chemical composition, yield, and DPPH radical scavenging activity of the obtained essential oils were evaluated. The composition of the essential oils was determined with gas chromatography-mass spectrometry and gas chromatography-flame ionization detection analyses. The influence of drying on the chemical composition of the essential oils of L. thymoides was evaluated by multivariate analysis, and their antioxidant activity was investigated via the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The Midilli model was the most appropriate to describe the behavior of drying kinetic data of L. thymoides leaves. Thymol was the major compound for all analyzed conditions; the maximum content was obtained from fresh leaves (62.78 ± 0.63%). The essential oils showed DPPH radical scavenging activity with an average of 73.10 ± 12.08%, and the fresh leaves showed higher inhibition (89.97 ± 0.31%). This is the first study to evaluate the influence of drying on the chemical composition and antioxidant activity of L. thymoides essential oils rich in thymol.
Keywords:drying kinetics  thymol  yield  multivariate analysis  DPPH
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