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Raman spectroscopy of gold nanoparticle conjugates of cosmetic ingredient kinetin
Institution:1. Department of Chemistry, Soongsil University, Sangdo-dong, Dongjak-gu, Seoul 156-743, South Korea;2. School of Systems Biomedical Science, Soongsil University, Sangdo-dong, Dongjak-gu, Seoul, South Korea;3. Department of Electrical Engineering, Soongsil University, Seoul 156-743, South Korea;1. Toyota Physical and Chemical Research Institute, Nagakute, Aichi 480-1192, Japan;2. Ceramics and Biomaterials Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam;3. Institute of Research and Development, Duy Tan University, Da Nang, Vietnam;4. Toyota Central R&D Labs., Inc., Nagakute, Aichi 480-1118, Japan;5. High Field NMR Group, National Institute for Material Science, Tsukuba, Ibaraki 305-0003, Japan;1. Tan Trao University, Tuyen Quang, Viet Nam;2. VNU University of Science, Ha Noi, Viet Nam;3. Duy Tan University, Da Nang, Viet Nam;1. School of Chemistry and Chemical Engineering, Key Laboratory for Green Process of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi 832003, China;2. State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Sciences, Taiyuan 030001, China;3. School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
Abstract:We performed a feasibility test of the cosmetic ingredient kinetin (KT)-gold nanoparticle (AuNP) conjugates by means of vibrational Raman spectroscopy and quantum mechanical calculations. The adsorptions of KT on AuNP surfaces were examined by absorption spectra and surface-enhanced Raman scattering (SERS). The size of KT at the initial concentrations of 10−5 M with the AuNP composites was measured to be 22 nm. Density functional theory (DFT) calculations were performed to estimate the energetic stabilities of KT on an Au cluster atom. The two tautomeric forms of 9H-amino and 7H-amino in KT are predicted to have similar energies on Au. The N3-coordinating geometries in both 9H-amino and 7H-amino forms of KT are predicted to be most stable on an Au cluster. Vibrational analysis also suggested that the two tautomers of KT should coexist in the adsorbed state on Au. The concentration-dependent SERS spectra of KT indicated that 5 × 10−5 M exhibited the highest SERS signals.
Keywords:Gold nanoparticles  Adsorption  Density functional theory  Raman spectroscopy  Kinetin
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