CHEMICAL BEHAVIOR OF SOME BENZ[b] INDENO[1,2-e] [1,4] THIAZINE DERIVATIVES |
| |
| Authors: | Gaetano Liso Antonia Reho Giuseppe Trapani Franco Micheletti Moracci |
| |
| Institution: | 1. Istituto di Chimica Organica, Facoltà di Farmacia , Università di Bari , Bari, Italy;2. Cattedra di Chimica Farmaceutica Applicata , Università di Roma , Rome, Italy |
| |
| Abstract: | Abstract The study of the chemical behavior of some benzb] indeno1,2-e] 1,4] thiazine derivatives was accomplished. Different reactivities were observed for 4b,5-dihydrobenzb]-indeno1,2-e] 1,4] thiazine-10α(11H)-ol (3) and 5-ethyl-4b,5-dihydrobenzb] indeno1,2-e]-1,4] thiazine-10α(11H)-ol (5); 3 is reoxidated to benzb] indeno1,2-e] 1,4] thiazine-10α(11H)-ol (2), while 5 undergoes transposition and oxidation to spiro3-ethylbenzo-thiazol-2(3H), 1′-indan-2′-one] (6). Possible pathways for these transformations are discussed. |
| |
| Keywords: | |
|
|
