| Abstract: | A flow injection spectrophotometric procedure with symmetric merging zones for dipyrone determination in pharmaceutical formulations is proposed. The determination is based on the formation of a blue complex (monitored at a wavelength of 642 nm) yield in the complexation reaction of dipyrone with Fe(III) in acid medium. Under optimum conditions, a calibration curve was obtained from 3.5 to 281 mg L?1 with a detection limit of 2.8 mg L?1 and the samples throughput was 80 h?1. The analytical results obtained for commercial formulation samples by applying the proposed method were in good agreement with labeled values and those obtained by a comparative procedure at a 95% confidence level. |
