Determination of climbazol in shampoos by reversed-phase liquid chromatography |
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| Authors: | L. Gagliardi L. Turchetto A. Amato D. Tonelli |
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| Affiliation: | Istituto Superiore di Sanità, Rome Italy;Istituto di Scienze Chimiche, Università di Bologna, Via San Donato 15, 40127 Bologna Italy |
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| Abstract: | ![]()
A method based on ior-pair reversed-phase liquid chromatography is reported for the determination of climbazol, a preservative used in cosmetic products. The column was packed wit LiChrosob RP-18, the mobile phase was acetonitrile-sodium perchlorate (0.05 M, pH 3.0) (40 + 60) and detection was at 224 nm. The method was applied to the analysis of commercial shampoos. The detection limit was 10 ng injected and calibration linearity was observed up to 6 μg. |
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| Keywords: | Climbazol Shampoo Cosmetics |
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