|
|||||
|
|
Evaluation of isothermal kinetic of sweetener |
|
| Authors: | Marta M?Concei&#;&#;o V J?Fernandes Jr F S M?Sinfr&#;nio J C O?Santos M C D?Silva V M?Fonseca A G?Souza |
| Institution: | (1) Universidade Federal do Rio Grande do Norte, CCET, Natal, RN, Brazil;(2) Universidade Federal do Rio Grande do Norte, CCET, Natal, RN, Brazil;(3) Universidade Federal da Paraíba, Departamento de Química, PB, Brazil;(4) Universidade Estadual da Paraíba, Campina Grande, PB, Brazil;(5) Universidade Federal da Paraíba, Departamento de Química, PB, Brazil;(6) Universidade Federal de Campina Grande, Campina Grande, PB, Brazil;(7) Universidade Federal da Paraíba, Departamento de Química, PB, Brazil |
| Abstract: | Summary Sulfonylureas are widely used for the treatment of non-insulin dependent diabetes mellitus. Glibenclamide belongs to the group of substituted arylsulfonylureas. Many representative of this group shows polymorphism. The purpose of this work was to investigate the thermal behaviour and compatibility between glibenclamide and some excipients using thermoanalytical techniques (TG-DTG/DSC). The thermal and isothermal kinetics data showed incompatibility between glibenclamide and magnesium stearate. |
| Keywords: | thermogravimetry kinetic analysis aspartame sweetener |
| 本文献已被 SpringerLink 等数据库收录！ | |