New Dammarane‐Type Saponins from the Roots of Panax notoginseng |
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| Authors: | Li Qiu Yang Jiao Gui‐Kun Huang Ji‐Zhao Xie Jian‐Hua Miao Xin‐Sheng Yao |
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| Institution: | 1. Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, Guangdong, P.?R. China (phone/fax: +86‐20‐85225849);2. Institute of Guangxi Medicinal Plant, Nanning 530023, Guangxi, P.?R. China;3. School of Pharmaceutical Science, Guangxi Medical University, Nanning 530021, Guangxi, P.?R. China |
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| Abstract: | Three new dammarane‐type triterpenoid saponins, 1 – 3 , were isolated and identified as (20S)‐20‐O‐β‐D ‐xylopyranosyl‐(1→6)‐β‐D ‐glucopyranosyl‐(1→6)‐β‐D ‐glucopyranosyl]dammar‐24‐ene‐3β,6α,12β, 20‐tetrol ( 1 ), (20S)‐6‐O‐(E)‐but‐2‐enoyl‐(1→6)‐β‐D ‐glucopyranosyl]dammar‐24‐ene‐3β,6α,12β,20‐tetrol ( 2 ), and (20S)‐6‐O‐β‐D ‐xylopyranosyl‐(1→2)‐β‐D ‐xylopyranosyl]dammar‐24‐ene‐3β,6α,12β,20‐tetrol ( 3 ) from the roots of Panax notoginseng (Burkill ) F.H.Chen (Araliaceae). Their structures were elucidated on the basis of spectroscopic analyses, including 1D‐ and 2D‐NMR techniques and HR‐ESI‐MS, as well as by acidic hydrolysis. |
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| Keywords: | Panax notoginseng Dammarane Saponins Notoginsenoside Ginsenosides |
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