Three New Triterpene Saponins from Bolbostemma paniculatum |
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| Authors: | Yun Tang Jia‐Qing Cao Wei Li Wei Li Yu‐Qing Zhao |
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| Affiliation: | 1. School of Traditional Chinese Materia Medica 51#, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, P.?R. China (phone/fax: +86‐24‐23986521);2. Key Laboratory of Jiangxi Province Natural Active Pharmaceutical Ingredients, College of Chemistry and Biology Engineering, Yichun University, Yichun 336000, P.?R. China |
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| Abstract: | Two novel noroleanane saponins, tubeimoside A ( 1 ) and tubeimoside B ( 2 ), and a new dammarane triterpene saponin, tubeimoside C ( 3 ), together with two known compounds, 4 and 5 , were isolated from the bulbs of Bolbostemma paniculatum (Maxim .) Franquet . Compound 4 was found in this genus for the first time. Based on spectroscopic methods, including IR, NMR (DEPT, COSY, HMQC, HMBC, and TOCSY), and MS experiments, and chemical reactions, the structures of the new compounds were elucidated as 3β‐[β‐D ‐glucopyranosyl‐(1→2)‐β‐D ‐glucopyranosyloxy]‐2β,23‐dihydroxy‐28‐norolean‐12‐en‐16‐one ( 1 ), 3β‐[β‐D ‐glucopyranosyl‐(1→2)‐β‐D ‐glucopyranosyloxy]‐2β,23‐dihydroxy‐28‐norolean‐12‐en‐22‐one ( 2 ), (3β,7β)‐7,18,20‐trihydroxydammar‐24‐en‐3‐yl 2‐O‐α‐L ‐arabinopyranosyl‐β‐D ‐glucopyranoside ( 3 ). |
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| Keywords: | Bolbostemma paniculatum Noroleanane saponins Saponins Triterpenoids Tubeimosides A and B |
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