Iodine‐Catalyzed Synthesis of Spiro[1,3,4‐benzotriazepine‐2,3′‐indole]‐2′,5(1H,1′H)‐diones under Mild Conditions |
| |
| Authors: | Abdolali Alizadeh Javad Mokhtari |
| |
| Affiliation: | 1. Department of Chemistry, Tarbiat Modares University, P.O. Box 14115‐175, Tehran, Iran (phone: +98‐21‐88006631;2. fax: +98‐21‐88006544) |
| |
| Abstract: | The I2‐catalyzed preparation of spiro[1,3,4‐benzotriazepine‐2,3′‐indole]‐2′,5(1H,1′H)‐diones from 2‐aminobenzohydrazide and isatins in MeCN at room temperature in good‐to‐excellent yields is described. The structure of 3 was corroborated spectroscopically (IR, 1H‐ and 13C‐NMR, and EI‐MS data). A plausible mechanism for this type of reaction is proposed (Scheme 2). |
| |
| Keywords: | Iodine catalysis Spiro[1,3,4‐benzotriazepine‐2,3′ ‐indole]‐2′ ,5(1H,1′ H)‐diones Isatins Benzohydrazide, 2‐amino‐ |
|
|
