Synthesis and biological activity of permethrin analogs containing various substituents in position <Emphasis Type="Italic">2</Emphasis> of the cyclopropane ring |
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| Authors: | N S Mirzabekova N E Kuz’mina O I Lukashov N A Sokolova S N Golosov P V Kazakov T G Perlova V V Potapova V A Kheinman G B Ivanova |
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| Institution: | (1) State Research Institute of Organic Chemistry and Technology, shosse Entuziastov 23, Moscow, 111024, Russia;(2) All-Russian Research Institute of Chemical Means for Plant Protection, Moscow, Russia |
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| Abstract: | A number of permethrin derivatives having various substituents (Me, Et, Pr, Ph, PhCH2, PhCH2CH2) in position 2 of the cyclopropane ring were synthesized and assayed for insecticidal activity against typhoid flies, rice weevils, and black bean aphid and juvenile hormone activity against flour beetle chrysalises. The examined compounds showed a weak insecticidal activity. Some derivatives were found to exert knockdown effect analogous to that of commercial pyrethroid tetramethrin; however, unlike permethrin, they exhibited pronounced juvenile hormone activity. |
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