Acetogenins in Annona muricata L. (annonaceae) leaves are potent molluscicides |
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| Authors: | Luna J De S De Carvalho J M De Lima M R F Bieber L W Bento Edson De S Franck X Sant'ana A E G |
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| Institution: | Departamento de Química Fundamental, Universidade Federal de Pernambuco, 50.740-901 Recife-PE, Brazil. |
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| Abstract: | An ethanolic extract of the leaves of Annona muricata was shown to be toxic to adult forms of the snail Biomphalaria glabrata (LC50 9.32 microg mL(-1)) and to larvae of the brine shrimp Artemia salina (LC50 0.49 microg mL(-1)). Activity-guided fractionation of the extract gave rise to a sample with high molluscicidal activity that contained the acetogenins, annonacin (90%), isoannonacin (6%) and goniothalamicin (4%). |
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