Efficient one-pot synthesis of substituted pyrazoles |
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| Authors: | Meng Tang Fu-Min Zhang |
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| Institution: | 1. School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China;2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China |
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| Abstract: | An efficient, one-pot synthesis of substituted pyrazoles from enones, hydrazides, and halides was developed. In comparison with the classical Knorr pyrazole synthesis, this methodology gave a different type of product (R3≥R5). A range of substituted pyrazoles were prepared in good to high yields with complete regioselectivity. |
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