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2,3‐Diaryl‐3‐hydroxy­propionic acid inter­mediates in the synthesis of threo forms of 1,2‐diaryl‐1,3‐propane­diols
Authors:Rolf Stomberg  Vratislav Langer  Knut Lundquist
Abstract:Racemic threo‐3‐hydroxy‐2,3‐diphenyl­propionic acid, C15H14O3, (I), crystallizes from ethyl acetate as a conglomerate of separate (+)‐ and (−)‐crystals. The geometries of (I) and its methyl ester are compared. Reduction of (I) gives threo‐1,2‐diphenyl‐1,3‐propane­diol. The synthesis of threo forms of 1,2‐diaryl‐1,3‐propane­diols via 2,3‐diaryl‐3‐hydroxy­propionic acids is discussed.
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