基于偏振滤波的皮肤镜光学和机械设计

皮肤镜在临床中已广泛用于诊断皮肤病变,然而,如何更加清晰准确地观察表皮、真皮表皮交界处和真皮乳头层内的色素性结构的大小、形状、颜色的深浅及浅层血管丛血管的大小形态依旧是一个挑战。由于皮肤表皮层类似于镜面反射,不改变反射光的偏振态,而皮肤组织表皮层以下的组织会改变原有光线的偏振态,基于此,本文设计了一个视场为22 mm、倍率为10×的手持偏振皮肤镜,通过采用偏振照明成像技术可以更加清晰有效地观察深层皮肤组织的病变以及病变组织形态,从而提高临床诊断与鉴别效率。

Optical and mechanical design of polarization filtered dermoscopy

Dermoscopy has been widely used in the diagnosis of skin lesions in the clinical field.However,difficulty remains in clear and accurate observation of the size,shape,color depth and size of superficial vascular plexus vessels in the epidermis,dermal-epidermal junction and dermal papilla.Since the epidermis is specularly reflective,it does not change the polarization state of the reflected light.Contrarily,tissue below the epidermal layer of the skin tissue changes the polarization state of the source light.Based on this,we designed a handheld system with a field of view of 22 mm and a magnification of 10×that performs polarized dermoscopy through the use of polarized illumination imaging technology,which more clearly and effectively observe the lesions of deep skin tissue and the morphology of lesions,thereby improving the efficiency of clinical diagnoses.