Development of [3]ferrocenophane-derived N/B frustrated Lewis pairs for the metal-free catalytic hydrogenation of imines |
| |
| Authors: | Zhentao Pan Hui Wang Fei Ling Lian Xiao Dingguo Song |
| |
| Affiliation: | Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China |
| |
| Abstract: | A series of novel [3]ferrocenophane-derived N/B frustrated Lewis pairs (FLPs) were synthesized and successfully applied to the catalytic hydrogenation of imines in 71–93% yields. This approach could be easily conducted on gram scale and provided versatile synthetic route for the key intermediate of sertraline hydrochloride without heavy metal residues. |
| |
| Keywords: | Ferrocenophane frustrated Lewis pairs hydrogenation imine metal-free |
|
