Recent synthetic methodologies for pyrazolo[1,5-a]pyrimidine |
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| Authors: | Mohamed A. Salem Mohamed H. Helal Moustafa A. Gouda Hala H. Abd EL-Gawad Marwa A. M. Shehab Abeer El-Khalafawy |
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| Affiliation: | 1. Department of Chemistry, Faculty of Science and Arts, King Khalid University, Mohail Asir, Saudi Arabia;2. Department of Chemistry, Faculty of Arts and Science, Northern Border University, Rafha, Saudi Arabia;3. Department of Chemistry, Faculty of Science and Arts, Ulla Taibah University, Medina, Saudi Arabia;4. Department of Chemistry, Faculty of Science, King Khalid University, Abha, Saudi Arabia |
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| Abstract: | The development of new synthetic routes towards pyrazolo[1,5-a]pyrimidines for their biological and medicinal exploration is an attractive area for researchers. This review focuses on various synthetic routes developed in the last decade for the synthesis of differently substituted pyrazolo[1,5-a]pyrimidines by a broad range of organic reactions by means of 5-aminopyrazole as a precursor. |
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| Keywords: | 5-Aminopyrazole enaminonitriles pyrazolo[1,5-a]pyrimidines α,β-unsaturated ketones β-diketones β-ketoester |
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