An unexpected, novel, three-component reaction between isoquinoline, an isocyanide and strong CH-acids in water |
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| Authors: | Ahmad Shaabani Ebrahim Soleimani Hamid Reza Khavasi |
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| Affiliation: | Department of Chemistry, Shahid Beheshti University, PO Box 19396-4716, Tehran, Iran |
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| Abstract: | An unexpected three-component condensation reaction between an isocyanide, isoquinoline and a strong CH-acid efficiently provides 1,2-dihydroisoquinoline derivatives in a one-pot reaction in water at 70 °C without using any catalyst. |
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| Keywords: | 1,2-Dihydroisoquinoline Isoquinoline Isocyanide Multi-component reactions |
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