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An approach for quinolines via palladium-catalyzed Heck coupling followed by cyclization |
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| Authors: | Chan Sik Cho Jun Uk Kim |
| Affiliation: | a Research Institute of Industrial Technology, Kyungpook National University, Daegu 702-701, South Korea b Department of Applied Chemistry, Kyungpook National University, Daegu 702-701, South Korea |
| Abstract: | 2-Iodoaniline reacts with α,β-unsaturated carbonyl compounds in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst along with a base to afford the corresponding quinolones or quinolines in moderate to good yields. |
| Keywords: | Alkenes Cyclization Heck reaction Quinolines Quinolones Palladium catalyst |
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