Transition-metal-free oxidative amidation of benzyl alcohols with amines catalyzed by NaI: a new method for the synthesis of benzamides |
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| Authors: | Meghdad Karimi Dariush Saberi Kobra Azizi Marzban Arefi Akbar Heydari |
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| Affiliation: | 1. Chemistry Department, Tarbiat Modares University, PO Box 14155-4838, Tehran, Iran;2. Fisheries and Aquaculture Department, College of Agriculture and Natural Resources, Persian Gulf University, 75169 Bushehr, Iran |
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| Abstract: | ![]()
A simple, inexpensive, and efficient method for the synthesis of benzamides via the reaction of benzyl alcohols and amine hydrochloride salts in the presence of NaI as a green catalyst is described. Various derivatives of benzamide were synthesized in moderate to good yields using this method. |
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| Keywords: | Benzyl alcohol Amine Oxidative amidation Sodium iodide |
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