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Arylation of aryl chlorides,a convenient method for the synthesis of new potential triazolic fungicides
Authors:Natividad Herrera Cano  Ana N. Santiago
Affiliation:INFIQC, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, Córdoba 5000, Argentina
Abstract:We evaluated two alternative routes for the arylation of known chlorinated fungicides. The first pathway involved a SRN1 substitution, followed by Stille reaction, while the second consisted in a one step reaction by the Suzuki coupling. Both methodologies were useful to obtain new products that could be potential fungicides.
Keywords:Electron transfer   Herbicide   Thiolate group   DFT
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