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Facile synthesis of 1,2,4-triazolines via PPh3-triggered reaction of azodicarboxylate with 2-azidoacrylates |
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| Authors: | Deng HongYuanxun Zhu Xufeng Lin Yanguang Wang |
| Institution: | Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China |
| Abstract: | A convenient method for the synthesis of 1,2,4-triazolines by triphenylphosphine-triggered reaction of dialkyl azodicarboxylate with 2-azidoacrylates is described. The cascade reaction procedure is general and efficient. |
| Keywords: | Huisgen zwitterion Triazoline Azidoacrylates Cascade reaction Heterocycle |
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