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Measuring vitamins and minerals in dietary supplements for nutrition studies in the USA
Authors:Johanna T. Dwyer  Joanne Holden  Karen Andrews  Janet Roseland  Cuiwei Zhao  Amy Schweitzer  Charles R. Perry  James Harnly  Wayne R. Wolf  Mary Frances Picciano  Kenneth D. Fisher  Leila G. Saldanha  Elizabeth A. Yetley  Joseph M. Betz  Paul M. Coates  John A. Milner  Jackie Whitted  Vicki Burt  Kathy Radimer  Jaime Wilger  Katherine E. Sharpless  Constance J. Hardy
Affiliation:(1) Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA;(2) Nutritional Sciences Research Group, National Cancer Institute, US Department of Health and Human Services, Bethesda, MD 20892, USA;(3) National Health and Nutrition Examination Survey, National Center for Health Statistics, Centers for Disease Control and Prevention, US Department of Health and Human Services, Hyattsville, MD 20782, USA;(4) National Institute of Standards and Technology, Gaithersburg, MD 20899, USA;(5) Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705, USA;(6) Food Composition Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705, USA;(7) Research and Development Division, National Agricultural Statistics Service, US Department of Agriculture, Fairfax, VA 22030, USA;(8) Center for Food Safety and Applied Nutrition, Food and Drug Administration, US Department of Health and Human Services, Rockville, MD 20850, USA
Abstract:
This article illustrates the importance of having analytical data on the vitamin and mineral contents of dietary supplements in nutrition studies, and describes efforts to develop an analytically validated dietary supplement ingredient database (DSID) by a consortium of federal agencies in the USA. Preliminary studies of multivitamin mineral supplements marketed in the USA that were analyzed as candidates for the DSID are summarized. Challenges are summarized, possible future directions are outlined, and some related programs at the Office of Dietary Supplements, National Institutes of Health are described. The DSID should be helpful to researchers in assessing relationships between intakes of vitamins and minerals and health outcomes.
Keywords:Dietary supplements  Dietary supplement ingredient database  Multivitamin mineral supplements  Analytical values
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