酶促开环聚合和原子转移自由基聚合制备新型H型嵌段共聚物

在生物酶催化剂Novozyme-435的作用下, 乙二醇引发己内酯(ε-CL)酶促开环聚合, 再用三乙胺作催化剂, 将PCL端羟基与2,2-二氯代乙酰氯反应, 生成四官能度大分子引发剂, 引发甲基丙烯酸环氧丙酯(GMA)的原子转移自由基聚合(ATRP), 合成了H型三嵌段共聚物(PGMA)2-b-PCL-b-(PGMA)2. 嵌段共聚物的结构通过核磁共振和凝胶渗透色谱(GPC)得到了确证, 其多分散性为1.32, 分子量为32000. 通过差热扫描量热法对嵌段共聚物的热性能进行了研究.

Synthesis of Novel H-shaped Block Copolymer by the Combination of Enzymatic-Promoting Ring-opening Polymerization and ATRP

Enzymatic-promoting ring-opening polymerization(ROP) of ε-caprolactone(ε-CL) was performed in the presence of biocatalyst Novozyme-435 and initiator ethylene glycol. The resulting polymer was esterified with 2,2-Dichloro acetyl chloride(DCAC) to obtain macroinitiator, which can be used in the following ATRP of the glycidyl methacrylate(GMA) using CuCl/2,2’-bipyridine as the catalyst system to synthesize the well-defined H-shaped block copolymer(PGMA)2-b-PCL-b-(PGMA)2. The structure of the polymer was characterized via GPC and 1H NMR analysis. The polydisperisty of the resulting H-shaped block copolymer is 1.32, Mn=32000. The thermal properties of block copolymer was characterized by differential scanning calorimetry.